右美托咪定不同给药途径对患者术后恢复影响的研究进展

Research progress on effect of different routes of dexmedetomidine administration on postoperative recovery

中文关键词: 右美托咪定  术后恢复  给药途径  加速术后康复

英文关键词: Dexmedetomidine  Postoperative recovery  Routes of administration  Enhanced recovery after surgery

中文摘要:

      右美托咪定是一种高选择性的α₂肾上腺素受体激动药，具有广泛的镇静、镇痛、催眠等效应，且相关不良反应较少，适用于丰富的临床场景。但不同的给药途径，如静脉给药、鼻内给药、口服给药、神经阻滞等，其使用剂量及不良反应等可能会存在差异，对于术后恢复的影响也不尽相同。本综述将系统阐述右美托咪定在不同给药途径下的临床情景并分析对术后恢复的影响，旨在为麻醉科医师提供更科学、更合理的用药参考。

英文摘要:

      Dexmedetomidine is a highly selective α₂ adrenoceptor agonist with a wide range of sedative, analgesic, and hypnotic effects and fewer associated adverse effects. This makes it suitable for various clinical scenarios. However, different routes of administration, such as intravenous, intranasal, oral, and nerve block, may vary in specific dosages and adverse reactions, and their impact on postoperative recovery may also differ. This review will systematically analyze the clinical scenarios of dexmedetomidine under different routes of administration and its impact on postoperative recovery, aiming to provide clinicians and anesthetists with more scientific and rational drug choices.